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Purine salvage promotes treatment resistance in H3K27M-mutant diffuse midline glioma

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Abstract Background Diffuse midline gliomas (DMG). including diffuse intrinsic pontine gliomas (DIPGs). are a fatal form of brain cancer. These tumors often carry a driver mutation on histone H3 converting lysine 27 to methionine (H3K27M). https://www.tipsfromatypicalmom.com/product-category/womens-footwear/
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